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Temsirolimus is an ester analog of rapamycin. It binds to and inhibits the mammalian target of rapamycin (mTOR),

依維莫司 Everolimus Everolimus, also known as RAD001, is a derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties.

曲美替尼 Trametinib Trametinib, also known as GSK1120212, is a n orally bioavailable inhibitor of mitogen-activated protein kinase kinase (MEK MAPK/ERK kinase) with potential antineoplastic activity.

考比替尼 Cobimetinib Cobimetinib, also known as GDC-0973 and XL-518, RG 7420, is an orally bioavailable small-molecule inhibitor of mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1)

貝美替尼 Binimetinib Binimetinib, also known as MEK162 (ARRY-162), is an oral, highly selective MEK inhibitor.